Curricular Unit:Code:
Human Physiopathology1080FPHU
2UndergraduateNutrition Sciences4 ects
Learning Period:Language of Instruction:Total Hours:
Winter SemesterPortuguese/English52
Learning Outcomes of the Curricular Unit:
Physiopathology has as main objective the acquisition of knowledge about the etiopathogenesis of several pathological clinical entities considered relevant for this professional area.
With this type of lectures, is expected that students acquire knowledge that will allow them to understand several topics essential for professional practice.
Contents will be adapted to the requirements of the degree and will be complemented by research, assuming students a relevant role in the elaboration of a bibliographic support importante for study and evaluation process.
Taking into account the specific characteristics of the topics, students will be encouraged to make a continuous preparation, based on the consultation of excerpts from scientific books and articles.
CP1.Inflammation and repair. Acute, chronic and granulomatous inflammation.
CP2. Cell proliferation and differentiation. Cell cycle regulation. Necrosis and apoptosis.
CP3.Cellular aggression. Atrophy, hypertrophy, hyperplasia and metaplasia. Reversible and irreversible injuries.
CP4.Atherosclerosis. Atheroma plaque as model. Implications for vascular physiology and strokes.
CP5.Immunopathology. Human immunodeficiency virus as a model.
CP6.Malabsorption and malnutrition. Celiac disease as a model.
CP7.Dietary imbalances. Hypometabolic, hypermetabolic and mixed problems. Pancreatitis, diabetes and chronic liver disease.
CP8.Neoplasms. Oncogenes, suppressor genes. Tumor initiation, promotion and progression.
CP9.Most common tumor types. Particular aspects.
CP10.Environmental carcinogenesis. Carcinogenesis in the respiratory and digestive systems.
CP11.Carcinogenesis of the upper and lower digestive tract. Importance of the microbiome.
CP12.Pathophysiology of aging.
Demonstration of the Syllabus Coherence with the Curricular Unit's Objectives:
OA1.Analyze the mechanisms of inflammation and cell repair.
OA2.Learn about cell proliferation and differentiation, cell cycle regulation, necrosis and apoptosis.
OA3.Understand how cells react to aggressions. Atrophy, hypertrophy, hyperplasy and metaplasy, reversible and irreversible damage.
OA4.Learn mechanisms underlying the process of atherogenesis and implications for vascular physiology and strokes.
OA5. Teach and learn about immunopathology based on the human immunodeficiency virus.
OA6.Understand the importance of malabsorption in malnutrition.
OA7.Understanding the pathophysiology of food imbalances and their importance.
OA8. Introduction to oncogenesis and cancer susceptibility.
OA9.Describe the most frequent types of neoplasms.
OA10.Learn environmental carcinogenesis and its intervention in some tumors.
OA11.Analyze carcinogenesis of upper and lower digestive tracts.
OA12.Analyze pathophysiology of the aging process.
Teaching Methodologies (Including Evaluation):
Teaching and learning in classroom will be carried in an expositive way during theoretical lectures each during 2 hours.
Several organic functions and dysfunctions involved in pathologies will be approached in detailed and systematic methodology.
Evaluation will be made by two tests, including multiple-choice, true / false and development questions.
Final classification of the component will be the result of the arithmetic average of partial classifications.
A final exam will be realized for students who have not opted for continuous evaluation or who have not been able to obtain a positive classification in continuous option.
Demonstration of the Coherence between the Teaching Methodologies and the Learning Outcomes:
Learning methodology, were lectures are complemented with discussion of clinical cases, help the comprehension about all the themes enumerated in the pedagogic plain. Coherence between topics (CP) and learning objectives (AO) can be analyzed in the correspondence between contents.
1. Frank H Netter; Atlas de Fisiologia Humana.
2. Textbook of Medical Physiology, Guyton & Hall’s.
Lecturer (* Responsible):
Eurico Monteiro (