Curricular Unit:			Code:
Biophysics and Biomechanics			1080BBIO
Year:	Level:	Course:	Credits:
1	Undergraduate	Nutrition Sciences	4 ects
Learning Period:		Language of Instruction:	Total Hours:
Spring Semester		Portuguese/English	52
Learning Outcomes of the Curricular Unit:
OA1. Define model. OA 2. Analyse the studied models. OA 3. Understand an exponential variation. OA 4. Apply the exponential variation to phenomena that occur in physiology and microbiology. OA 5. Understand the general mechanism of a regulatory phenomenon. OA 7. Apply the general mechanisms of control in the regulation of blood glucose and the rate of carbon dioxide in the blood. OA 8. Know how to explain simple processes of transporting matter. OA 9. To recognize the transport processes inherent in physiological phenomena. OA 10. Recognize the most important properties of blood as a fluid. OA 11. Apply the physical concepts of hydrodynamics to the blood circulation. OA 12. Understand and explain states of alteration to normal circulatory dynamics. OA 13. Explain the biophysics fundamentals of the neural conduction. AO 14. Apply bioimpedance concepts in the assessment of body composition.
Syllabus:
CP1 - Biophysics, objectives and methods. 1. 1. System. m. 1. 2. Models: the models of biological membranes. 1. 3. Exponential variations. CP2 - Regulation and control 2.1. Feedback cycle. 2.2. Stationary states: operating points. 2.3. Control cycles of blood glucose. CP3 - Transport phenomena 3.1. Passive transport: diffusion and osmosis 3.2. Active transport: sedimentation and active transport across membranes. CP4 - Fluid dynamics and blood circulation 4.1. Physical characteristics of blood fluid. 4.2. Heart and cardiac work. Pressure and flow. 4.2.1. The hydrostatic pressure of the blood. Debt conservation law. Bernoulli and Poiseuille law. 4.3 Study of phenomena at the capillary level. CP5 – Electricity and biopotentials. 5.1. Electricity basics 5.2. Bio potentials and electrical flow in the axon. 5.3. Bio impedance and body composition assessment.
Demonstration of the Syllabus Coherence with the Curricular Unit's Objectives:
CP1 - Biophysics, its objectives and methods. 1.1. and 1.2 - Aims to attain OA1 e OA2. 1. 3 - Aims to attain OA3 e OA4. CP2 - Regulation and control 2.1 to 2.4 - Aims to attain OA5, OA6 e OA7. 2.4 - Aims to attain OA8 and OA14. CP3 - Transport Phenomena 3.1 and 3.3 – Aims to attain OA8 e OA9. CP3 - Fluid Dynamics and Blood Circulation 4.1.1 - Aims to attain OA10. 4.1.2 to 4.2.4 - Aims to attain OA10. 4.2.5- Aims to attain OA11. 4.3 to 4.4 - Aims to attain OA12. CP5 – Nervous Influx Aims to attain OA1, OA2, OA5-OA7, OA13, OA14.
Teaching Methodologies (Including Evaluation):
M1 - Use of the e-learning platform to store educational material that will available to the student. M2 - The material provided will support part of the “based problems learning” M3 - Independent research activities that will be based on development and research issues. M4 - Development of basic contents synthesis activities, after oral presentation, where students will have a proactive involvement. M5 - The use of demonstration videos to visualise the continuous flow phenomena to promote the understanding of flow over the time. Evaluation Two summative assessment tests (30% and 60% of the final classification) + written work (10%). The summative evaluation will include a cognitive test (open question that demonstrates the student's understanding of the relevance of content to the course domains).
Demonstration of the Coherence between the Teaching Methodologies and the Learning Outcomes:
M1 - Use of the e-learning platform to store educational material that will available to the student: All the objectives M2 - The material provided will support part of the “based problems learning”: OA3, OA6, OA8, OA9 and OA14. M3 - Independent research activities that will be based on development and research issues: OA1, OA 2 e OA13. M4 - Development of basic contents synthesis activities, after oral presentation, where students will have a proactive involvement: All the objectives M5 - The use of demonstration videos of relevant techniques in nursing will also be used to promote the discussion of the physical fundamentals inherent to them: OA9, OA10 and OA14.
Reading:
Gomes, L.R.; Biofísica para Ciências da Saúde, Ed. Universidade Fernando Pessoa, 2012. da Silva, M.M., de Carvalho, R.S.M., de Freitas, M.B. (2019). Bioimpedância para avaliação da composição corporal: uma proposta didático-experimental para estudantes da área da saúde. Revista Brasileira de Ensino de Física, 41, 2, e20180271. Goñi, F. M. (2014). The basic structure and dynamics of cell membranes: An update of the Singer–Nicolson model. Biochimica et Biophysica Acta, 1838, 1467–1476. Franklin, K., Muir, P., Scott , T., Yates P. (2019). Introduction to Biological Physics for the Health and Life Sciences (2nd Ed.). John Wiley & Sons Inc, New York, United States. ISBN10 1118934504. Hobbie, R. K., Roth, B. J. (2015). Intermediate Physics for Medicine and Biology. Springer. ISBN 978-3-319-12682-1.