Curricular Unit:			Code:
Genetic Bases			1140BAGE
Year:	Level:	Course:	Credits:
1	Postgraduate	Pediatric Dentistry	1 ects
Learning Period:		Language of Instruction:	Total Hours:
		Portuguese/English	13
Learning Outcomes of the Curricular Unit:
The course focuses on the genetic bases involved in the development of the head as well as the genetic changes responsible for the development of several craniofacial malformations . Genetic syndromes that lead to changes in the oral cavity as well as some systemic diseases that give oral manifestations are also discussed. At last, the use of stem cells in the regeneration of dental tissues will also be discussed.
Syllabus:
1. Genetic bases of the development of the head 2. Genetic bases of craniofacial malformations 2.1. Lip and palatine cliff 2.2. Maloclusions 2.3. Craniosinostosis or Cranioestenosis 2.4. Ear anomalies 2.5. Ocular anomalies 2.6. Mandibular defects 2.7. Macrocefalia 2.8. Microcefalia 2.9. Dental anomalies 3. Genetic syndromes that lead to changes in the oral cavity 3.1. Chromosomal mutations A. Changes in the number of chromosomes B. Changes in the structure of chromosomes 3.2. Genetic mutations 4. Oral manifestations of systemic diseases 5. Tissue regeneration with stem cells 5.1. Types of stem cells 5.2. Tissue engineering
Demonstration of the Syllabus Coherence with the Curricular Unit's Objectives:
The syllabus comprising the curricular unit will meet the requirements that are set out in the objectives, and it provides students with the necessary lessons (concepts, techniques, methodologies) to be able to achieve the objectives set out above.
Teaching Methodologies (Including Evaluation):
The methodologies used are lecture, inductive and deductive methods.
Demonstration of the Coherence between the Teaching Methodologies and the Learning Outcomes:
The objectives of the curricular unit are achieved by the use of the methodology referred since the expository component provides guidance on the systematic study and the practice exercitation promotes the practical application of concepts and theories studied within the curricular unit.
Reading:
Cardoso JS et al. 2021. J Dent Oral Dis. 7(2), 1161. Lopes Cardoso I et al. 2020. J Med Care Res Rev, 3(9), 444-53. Leal MFC et al. 2020. Int J Appl Dental Sci, 6(3), 47-52. Leal MFC et al. 2020. Eur J Med Health Sci, 2(3), 1-11. Lopes Cardoso I et al. 2020. J Dent, Oral Dis Ther, 8(1), 8. Duque C, Lopes Cardoso I. 2019. Clin Res Trials, 5, 1-5. Noronha A, Lopes Cardoso I. 2018. J Med Biomed Appl Sci. 6(4):43-48. Gagliardi F, Cardoso IL. 2018. J Dental Craniofac Res. 3(1):1-4. Gonçalves M, Lopes Cardoso I. 2017. J Dental Oral Health Open Acc, 1:1-11.