Curricular Unit:			Code:
Pharmacodynamics			1080FARM
Year:	Level:	Course:	Credits:
3	Undergraduate	Nutrition Sciences	4 ects
Learning Period:		Language of Instruction:	Total Hours:
Spring Semester		Portuguese/English	52
Learning Outcomes of the Curricular Unit:
O1. Acquire the fundamentals of pharmacology in order to understand the drugs’ actions, from the level of a specific molecular target to the level of the patient. O2. Understand the mechanisms that govern the action of the most relevant drugs in the clinic and the actions of the pharmacologically active ingredients present in the foods that can alter the physiological, pathological or homeostatic mechanisms. O3 Identify the drug-food interactions, that is, understand the influence of pharmacological therapy on nutritional status and, equally, the influence of nutrients on the general cycle of action of drugs. O4. Transfer and adapt the knowledge of pharmacology to the practice of Nutrition Sciences, contributing to a more effective treatment of patients. O5. Acquire skills in searching for information on specific sources about drugs.
Syllabus:
CP 1. General Principles of Pharmacology. Drugs and pharmacological actions. General cycle of drugs in the organism (pharmacokinetics and pharmacodynamics) CP 2. Clinical Pharmacology 2.1 Pharmacology of the Central Nervous System 2.2 Pharmacology of the Autonomic Nervous System 2.3 Ethanol pharmacology 2.4 Anti-obesity drugs 2.5 Drugs affecting cardiovascular system 2.6 Drugs affecting gastrointestinal tract 2.7 Drugs affecting protein, carbohydrates and lipid metabolism CP 3. Pharmacology and Nutrition. Food-drug interaction. Nutraceuticals CP 4. Sources of drug information
Demonstration of the Syllabus Coherence with the Curricular Unit's Objectives:
CP 1. General Principles of Pharmacology - Correlates with O1. CP 2. Clinical Pharmacology - Correlates with O2 and O4. CP 3. Pharmacology and Nutrition. Food-drug interaction. Nutraceuticals - Correlates with O3 and O4. CP 4. Sources of drug information - Correlates with O5.
Teaching Methodologies (Including Evaluation):
M1. The pharmacological concepts will be discussed in the theoretical lectures and will focus on the most relevant therapeutic groups, by exposing the mechanisms of action, adverse effects and pharmacological interactions and using images and schemes that show these effects. Didactic material will be available on the e-learning platform. M2. Active participation of the student in the teaching-learning process, namely through the presentation/ discussion of practical cases related to drugs and their pharmacological interactions with clinical relevance, under teacher guidance. M3. Use of the main sources of drug information. Students will be driven in the search for information and, subsequently, are called to develop and present orally a project based on a bibliographical research work carried out in group. The acquisition of knowledge is verified through the accomplishment of two written tests (90%) and a bibliographic research work (10%).
Demonstration of the Coherence between the Teaching Methodologies and the Learning Outcomes:
M1. The pharmacological concepts will be discussed in the theoretical lectures and will focus on the most relevant therapeutic groups, by exposing the mechanisms of action, adverse effects and pharmacological interactions and by using images and schemes that show these effects. Didactic material will be available on the e-learning platform: O1-3. M2. Active participation of the student in the teaching-learning process, namely through the presentation/ discussion of practical cases related to drugs and their pharmacological interactions with clinical relevance, under teacher guidance: O1-4. M3. Use of the main sources of drug information. Students will be driven in the search for information and, subsequently, are called to develop and present orally a project based on a bibliographical research work carried out in group: O5
Reading:
1. Handbook of Drug–Nutrient Interactions, JI Boullata, VT Armenti (eds), 2nd edition, New Jersey, Human Press, 2010. ISBN 978-1-60327-362-6. 2. Goodman & Gilman´s The Pharmacological Basis of Therapeutics, L Brunton, B Knollmann e R Hilal-Dandan (Eds), 13th edition, McGraw-Hill, 2018. ISBN: 9781259584732. 3. Rang and Dale's pharmacology, J Ritter, R Flower, G Henderson, Y Loke, D MacEwan e H Rang. (Eds), 9th edition, Churchill Livingstone Elsevier, 2019. ISBN: 9780702074486. 4. Basic & Clinical Pharmacology, B Katzung (Ed), 14th edition, McGraw-Hill, 2018. ISBN: 9781259641152. 5. Terapêutica Medicamentosa e suas Bases Farmacológicas (Manual de Farmacologia e Farmacoterapia), S Guimarães, D Moura e P Soares da Silva (Eds), 6ª edição, Porto Editora, 2014. ISBN: 9789720017949.