Curricular Unit:			Code:
Physical Chemistry			843QF
Year:	Level:	Course:	Credits:
2	Master	Pharmaceutical Sciences	3 ects
Learning Period:		Language of Instruction:	Total Hours:
Spring Semester		Portuguese/English	39
Learning Outcomes of the Curricular Unit:
The discipline of Physical Chemistry aims to promote knowledge of different quantitative approaches to the study of chemical problems, making use of models and assumptions. Additionally, the knowledge of physical chemistry is applied to the study of various chemical systems, with emphasis on biological and biochemical systems
Syllabus:
Thermodynamics Basic concepts Thermodynamic language Types of systems and frontiers Zero principle of thermodynamics Boyle, Charles and Gay-lussac and Dalton Laws. Perfect Gases Equation First Law of Thermodynamics Work and Heat Expansion work. Reversible and Irreversible First Law of Thermodynamics Heat Capacities Thermochemistry Second Law of Thermodynamics Entropic Variations Third Law of Thermodynamics Gibbs and Helmholtz Energies Chemical Kinetics Rate Law Reaction order Half-life time Arrhenius equation Enzymatic kinetics Initial rate and maximum rate Michaelis-Menten equation and constant Michaelis-Menten equation linearization
Demonstration of the Syllabus Coherence with the Curricular Unit's Objectives:
The course aims to promote the knowledge of several quantitative approaches to study chemical problems, making use of models and postulates. Additionally, physical-chemistry knowledge is to be applied to the study of different chemical systems, with particular relevance to biological and biochemical processes. Students shall develop an active mentality in regards to different concepts in order to better value its correct use and understanding, either in other course subjects or in a future job.
Teaching Methodologies (Including Evaluation):
The unit comprises two parts, theoretical (T, 1h contact / week) and theoretical practice (TP, 1h contact / week). In class T, the topics are developed in contact time scheduled, using appropriate audio-visual equipment and emphasizing aspects that require the integration of concepts. Aditionaly deductions and demonstrations are presented using the black-board. At the end of the exposure of each subject questions are asked for debate. The evaluation is done by conducting two written tests T and two written tests TP. In class TP, theoretical aspects are deeper explored and application exercises are done. The global approval for the course requires approval from both components in a weighted average (67%T plus 33%TP).
Demonstration of the Coherence between the Teaching Methodologies and the Learning Outcomes:
The application of teaching methodologies in theoretical component aims at the acquisition and consolidation of knowledge in the technical and scientific field of the course, improve the ability to apply theoretical concepts to solve real problems and to guide the students for independent learning. The application of teaching methodologies in the practical component aims specifically to improve the capacity of solving thermodynamic and kinetic problems, the interpretation and critical analysis of results and to stimulate the habits of research and dependent learning.
Reading:
- Physical Chemistry; I.N. Levine; 4ª ed., McGraw-Hill; 1995 - Physical Chemistry; Barrow; 6ª ed., McGraw-Hill; 1996 - Physical Chemistry for the chemical and biological sciences; R. Chang; 3ª ed., University Science Books, 2000 - Physical Chemistry; P. Atkins e J. DePaula; 7ª ed., Freeman; 2001