Curricular Unit:Code:
Analytical Chemistry I843QAN1
2MasterPharmaceutical Sciences5 ects
Learning Period:Language of Instruction:Total Hours:
Winter SemesterPortuguese/English65
Learning Outcomes of the Curricular Unit:
Analytical Chemistry is an applied science that demands the learning and development of a series of principles, laws and techniques. It is eminently a measurement science, being an indispensable instrument of work with application in some areas of knowledge, including the health sciences, with innumerable examples in clinical chemistry, pharmaceutical analysis, in the control of the alimentary quality, in the control of the air, ground and water pollution and in the health and occupational security.
The main objective of this discipline is to transmit solid theoretical and practical basis in this area of knowledge. Concepts of the main steps in an analytical process, uncertainty associated with experimental data and solution equilibria (acid-base, precipitation, oxidation-reduction and complexation).
1. Introduction to Analytical Chemistry
2. Standard solutions and measurement of reagents
3. The Analytical Process
4. Experimental results – measurements, errors and significant figures
4. Fundamental concepts of chemical equilibrium
5. Acid-base equilibria
6. Precipitation equilibria
7. Complexometric equilibria
8. Redox equilibria
Demonstration of the Syllabus Coherence with the Curricular Unit's Objectives:
Analytical Chemistry has played a main role in the development of science. Understanding chemical equilibria is of prime importance for the correct implementation of many analytical procedures used in the determination of chemical species in several matrices. The aim of the theoretical component of this course is to provide a reliable knowledge of the fundamental concepts regarding chemical equilibria. The theoretical classes' material is applied and developed through a series of numerical problems, organized according to pre-established aims, that are accompanied in practical sessions. The purpose of laboratory practical classes is: to perform a series of experimental works whose completion will demonstrate some of the most important concepts studied and to allow the development of skills that enable the correct execution of the protocol, involving a sequence of steps that have to be performed in a given order, with final results having the lowest uncertainty possible.
Teaching Methodologies (Including Evaluation):
Methodologies (M): (M1) In the theoretical classes, the relevant T concepts are exposed and discussed and guidance for autonomous study is given. The principles associated with chemical equilibrium are studied and debated, using, whenever necessary, schemes and images. (M2) These contents are consolidated in practical classes dedicated to the resolution of questions of objective answer and numerical problems that allow the clarification of doubts and the deepening of specific topics. (M3) Active participation of the student in the teaching-learning process through the execution of a set of laboratory works.
Assessment: the acquisition of knowledge of the T component is validated through 2 written tests (70% of the final grade). The evaluation of the P component (30% in the final grade) will be based on laboratory performance, the quality of the results sheets delivered (50%) and 2 written tests (50%). TThe final classification will only be awarded if both components are approved.
Demonstration of the Coherence between the Teaching Methodologies and the Learning Outcomes:
At the end of this course, students should be able to recognize and describe the most important chemical reactions underlying contemporary quantitative analysis that enable them to understand their limitations/specificities. This allows the careful and strict control of all parameters that limit the quality of the analysis with the aim of obtaining results with adequate precision and accuracy. The fact that any chemical analysis involves a sequence of steps (whose execution mode has an influence in the result obtained) and that there is always some uncertainty associated with the final result in a quantitative analysis should be fully understood. All components of this course are linked and complement each other. Main concepts of chemical equilibria are given in theoretical classes. These theories are enhanced through the execution of a series of exercises proposed to students for resolution in practical classes. Students confirm all these theoretical principles in the laboratory practice component performing some experimental work chosen for this purpose.
Harris, D. C. e Lucy C. A. Quantitative Chemical Analysis, 10ª ed., W. H. Freeman, 2019. ISBN: 978-1319164300.
Souto, R., Pimenta, A. e Catarino, R. Manual Prático de Análise Química, Lusodidacta, 2018. ISBN: 978-9898075857.
Christian, G. D., Dasgupta, P. K. e Schug, A. Analytical Chemistry, 7ª ed, Wiley, 2013. ISBN: 978-0470887578.
Skoog D. A., West D. M., Holler, F. J. e Crouch S. R. Fundamentals of Analytical Chemistry, 9ª ed, Cengage Learning, 2013. ISBN: 978-0495558286.
Skoog, D. A., West, D. M., Holler, F. J. e Crouch, S. R. Fundamentos de Química Analítica, Tradução da 9ª ed. norte-americana, Cengage Learning, 2014. ISBN: 978-8522116607.
Lecturer (* Responsible):
Carla Sousa e Silva (
Renata Souto (