Curricular Unit:Code:
Theories of Senescence1032TSES
Year:Level:Course:Credits:
1MasterPhysiotherapy (Physiotherapy Elderly)6 ects
Learning Period:Language of Instruction:Total Hours:
Portuguese/English78
Learning Outcomes of the Curricular Unit:
-To know the theories of aging at the molecular, cellular, and tissue level of organs and systems
-Evolutionary Theories of Aging
-Integration of different theories
Syllabus:
-To know the theories of aging at the molecular, cellular, and tissue level of organs and systems
-Evolutionary Theories of Aging
-Integration of different theories
Demonstration of the Syllabus Coherence with the Curricular Unit's Objectives:
-The study of the different theories with more timeliness will allow to perceive the global process of the aging of the person at the physiological level the difference of the pathological aging.
Teaching Methodologies (Including Evaluation):
-Thematic and object ordering to be achieved by the teacher
-Bibliographic research by the student
-Exercise of cases by the student
-Discussion in group
-Resolution of doubts and repetition of objects in common
Demonstration of the Coherence between the Teaching Methodologies and the Learning Outcomes:
-Thematic and object ordering to be achieved by the teacher -Bibliographic research by the student -Exercise of cases by the student -Discussion in group -Resolution of doubts and repetition of objects in common
Reading:
- Comfort A. The biology of senescence. New York: Elsevier. 1979; 81-6.
- Wallace DC. Mitochondrial genetics: a paradigm for aging y degenerative diseases? Science 1992;
256:628-32.
- Miquel J, Fleming JE. A two-step hypothesis on the mechanism of in vitro cell aging cell differentiation
followed by intrinsic mitochondrial mutagenesis. Exp Gerontol. 1984; 19:31-6.- Harman D, Eddy DE. Free radical theory of aging: beneficial effect of adding antioxidants to the maternal
mouse diet on life span of offspring: possible explanation of the sex difference in longevity. En: Jonhson JE,
- Nohl H. Involvement of free radicals in ageing: a consequence or cause of senescence. Free Rad Med. 1993;
49(3):653-67
- Orgel LE. The maintenance of the accuracy of protein synthesis y its relevance to ageing. Proc Natl Acad Sci
USA. 1963; 49:517-21.
Dev. 1979; 10:371-7.
- Hayflick L, Moorhead PS. The serial cultivation of human diploid cell strains. Exp Cell Res 1961; 25:585-621.