Curricular Unit:Code:
Biophysics1019BFIS
Year:Level:Course:Credits:
1UndergraduateClinical Analyses and Public Health4 ects
Learning Period:Language of Instruction:Total Hours:
Spring SemesterPortuguese/English52
Learning Outcomes of the Curricular Unit:
OA
1. Define model, recognize its importance and conditionings.
2. Analyze the studied models, mention their applicability and restrictions.
3.Understand and analyse an exponential variation.
4.Apply the knowledge of the exponential variation to the explanation of exponential phenomena that occur in physiology and microbiology.
5.Understand the basic and general mechanism of a regulatory phenomenon.
7.Apply the general mechanisms of regulation and control to regulate blood glucose
8.Explain how body temperature control and the effects of hypothermia and hyperthermia.
9. Know how to explain simple processes of transporting matter
10. To recognize the transport processes inherent in physiological phenomena .
11.Recognize the properties of blood as a fluid.
12.Apply the physical concepts of hydrodynamics to the blood circulation.
13.Understand and explain states of alteration to normal circulatory dynamics
14. Explain the nervous flux
Syllabus:
Program content 1
CP1 - Biophysics, its objectives and methods.
1. 1. System definition. The human being as an open and regulated system.
1. 2. The use of analogies and models: the models of biological membranes.
1. 3. Exponential variations.
Programmatic content 2
CP2 - Regulation and control
2.1 Feedback Cycle.
2.2. Stationary states: operating points.
2.3. Regulation of a variable in proportional control. Body temperature control cycle
2.4. States of body temperature change
Programmatic content 3
CP3 - Transport Phenomena
3.1. Passive transport: diffusion and osmosis
3.2. Active transport: sedimentation and centrifugation, transport active by the membranes.
Programmatic content 4
CP4 - Fluid Dynamics and Blood Circulation
4.1. Heart and heart work. Pressure and flow.
4.2. Blood pressure
4.3. States of change in circulatory dynamics
CP5. The electrical impulse and the nervous flow.
Demonstration of the Syllabus Coherence with the Curricular Unit's Objectives:
CP1 - Biophysics, its objectives and methods.
1. 1. e 1.2 - correlates with OA1 e OA2.
1. 3. - correlates with OA3
1. 3. - correlates with OA4.
CP2 - Regulation and control
2.1 a 2. 4. - correlates with OA5, OA6 e OA7
2.4. - correlates with OA8
CP3 - Transport Phenomena
3.1 to 3.2 - correlates with OA9 and OA10
CP4 - Fluid Dynamics and Blood Circulation
4.1. - correlates with OA11
4.1. a 4.2 - correlates with OA11
4.2. correlates with OA11
4.3 a 4.4 - correlates with OA13
Teaching Methodologies (Including Evaluation):
M1 - Use of the e-learning platform to store educational material that will available to the student.
M2 - The material provided will support part of the “based problems learning”
M3 - Independent research activities that will be based on development and research issues.
M4 - Development of basic contents synthesis activities, after oral presentation, where students will have a proactive involvement.
M5 - The use of demonstration videos to visualise the continuous flow phenomena to promote the understanding of flow over the time.
Evaluation
Two summative assessment tests (50% each of the final classification). The summative evaluation will include a cognitive test (open question that demonstrates the student's understanding of the relevance of content to the course domains).
Demonstration of the Coherence between the Teaching Methodologies and the Learning Outcomes:
M1 - Use of the e-learning platform to store educational material that will available to the student: All the objectives M2 - The material provided will support part of the “based problems learning” : OA 3 a OA6 M3 - Independent research activities that will be based on development and research issues: OA1, OA 2 e OA13 M4 - Development of basic contents synthesis activities, after oral presentation, where students will have a proactive involvement: All the objectives M5 - The use of demonstration videos of relevant techniques in nursing will also be used to promote the discussion of the physical fundamentals inherent to them: OA9 e OA10
Reading:
Franklin, K., Muir, P., Scott , T., Yates P. (2019). Introduction to Biological Physics for the Health and Life Sciences (2nd Ed.). John Wiley & Sons Inc, New York, United States. ISBN10 1118934504.
Gomes, L.R.; Biofísica para Ciências da Saúde, Ed. Universidade Fernando Pessoa, 2012.
Félix M. Goñi. The basic structure and dynamics of cell membranes: An update of the
Singer–Nicolson model. Biochimica et Biophysica Acta 1838 (2014) 1467–1476.
Roland Glaser. Biophysics: An Introduction. Springer, 2nd ed. 2012.
Hobbie, Russell K., Roth, Bradley J. Intermediate Physics for Medicine and Biology. Springer, 2015. ISBN 978-3-319-12682-1