Curricular Unit:Code:
Analytical Chemistry II843QAN2
2MasterPharmaceutical Sciences5 ects
Learning Period:Language of Instruction:Total Hours:
Spring SemesterPortuguese/English65
Learning Outcomes of the Curricular Unit:
Analytical Chemistry is an applied science, mainly directed to quantitative chemical analysis that demands for the consistent knowledge of a series of theoretical principles.
There are numerous examples of analytical techniques in clinical chemistry, pharmaceutical industry, food quality control, control of air pollution, soil and water, health and safety.
Considering the skills acquired in Analytical Chemistry I, in Analytical Chemistry II major classical methods of quantitative analysis - volumetric analysis - will be addressed.
1. General consideration about quantitative analysis
2. General aspects about volumetric analysis
3. Acid-base titrations
4. Precipitation titrations
5. Complexometric titrations
6. Redox titrations
Demonstration of the Syllabus Coherence with the Curricular Unit's Objectives:
Nowadays, quantification of components present in a sample can be done either by traditional procedures or using an instrumental method of analysis. Volumetric analysis are undoubtedly the kind of classical quantitative analysis most frequently used. These methods are widely used for routine determinations because they are rapid, convenient, and accurate. Additionally, the knowledge of their inherent principles is essential for the understanding and correct use of the recent instrument methodologies.
Teaching Methodologies (Including Evaluation):
Explanation of main theoretical concepts and guidance for autonomous study will be given in theoretical classes. Titrimetric principles are carefully studied and discussed resorting to the use of charts, graphs and images. The material included in each chapter is studied in detail through through the execution of a series of numerical problems organized according to pre-established aims proposed to students for resolution under tutorial guidance. The theoretical components will be evaluate through the execution of tests (weighing coefficient of 70% in the final score).
Practical classes include the execution of a set of experimental works whose completion will demonstrate some of the most important concepts studied. The practical evaluation is based on the students’ performance, the quality of the reports delivered and the execution of two tests of practical nature. Final classification will be attributed only when all components are approved.
Demonstration of the Coherence between the Teaching Methodologies and the Learning Outcomes:
At the end of this course, students should be able to recognize and describe the several type of titrimetric analysis and know which experimental variables should controlled in order to obtain results with adequate precision and accuracy. Experimental treatment of data obtained should be clearly understood in order to appropriately process analytical signals to obtain species' concentration. Thus being, the course of Analytical Chemistry II is divided into two essential components that are linked and complement each other. Main concepts of quantitative determinations through volumetric analysis and UV/Vis spectrophotometry are given in theoretical classes. These theories are enhanced in the tutorial classes through the execution of a series of exercises. Students confirm all these theoretical principles in the laboratory practice component performing some experimental work chosen for this purpose.
Christian, G. D., Dasgupta, P. K. e Schug, K.A. (2014). Analytical Chemistry. 7ª ed., John Wiley & Sons.
Harris, D. C. e Lucy, C.A. (2019). Quantitative Chemical Analysis. 10ª ed., W. H. Freeman.
Souto, R. Pimenta, A. e Catarino, R. (2018) Manual Prático de Análise Química. 1ª ed. Lusodidacta.
Skoog, D. A., West, D.M., Holler, F.J., Crouch, S.R. (2021). Fundamentals of Analytical Chemistry. 10ª ed, Thomson-Brooks/Cole.