Curricular Unit:			Code:
General Microbiology			843MGER
Year:	Level:	Course:	Credits:
3	Master	Pharmaceutical Sciences	5 ects
Learning Period:		Language of Instruction:	Total Hours:
Winter Semester		Portuguese/English	65
Learning Outcomes of the Curricular Unit:
Identify the structural characteristics of prokaryotic, eukaryotic and virus cells; Identify the factors that influence the growth and metabolism of microorganisms. Describe the general principles of microbial genetics. Identify and describe the mechanisms of action of antimicrobials and antivirals. Identify and describe the basic mechanisms of the immune response, as well as the strategies of its modulation. Perform aseptic technique correctly; Use the optical microscope correctly; Understand the different coloring techniques for the observation of microorganisms; Understand and distinguish different methods for microbial identification; Perform and correctly interpret an antibiogram. Skills: To acquire habits of observation and critical analysis in the scope of Microbiology; Make decisions based on available scientific knowledge; Analyze bibliographical information critically.
Syllabus:
History of Microbiology   Main events and personalities in the area of Microbiology various roles of microorganisms Main groups of microorganisms: bacteria, fungi, protozoa and viruses.   Cellular organization of microorganisms.    Prokaryotes     Bacteria     Archaea    Eukaryotes   Virus    Ultra structure    Viral cycle Nutrition and growth of microorganisms   Nutritional requirements    Culture media   Multiplication and death of microbial populations    Growth kinetics.    Factors Affecting Bacterial Growth Antimicrobial Agents   Antibiotic Families    Mechanisms of action    Expectro activity    Mechanisms of resistance to antibiotics    Pharmacology     Pharmacokinetics and Pharmacodynamics     Adverse effects Biocides   Disinfectants and antiseptics Host-parasite relationship   Human Microbioma   Mechanisms of defense of the host   Microbial virulence factors
Demonstration of the Syllabus Coherence with the Curricular Unit's Objectives:
The program contents allow the knowledge of the various aspects of Microbiology. In addition to an introduction of environmental and historical context, a presentation is made of the basic structures of microorganisms in order to allow in the future to associate their characteristics with the possible effects on the human being as well as the environment that surrounds him. A study is made of the evolutionary component that allows microorganisms to adapt, to a greater or lesser extent, to the control mechanisms developed and applied by man. Finally students are exposed to a wide and varied number of interactions between microorganisms and their human hosts, ranging from the ability of microorganisms to survive to the defense capabilities of their hosts. These programmatic contents present a relevance for the proposed objectives, allowing with these resources to relate the diverse constituents of the microorganisms with their effects on the human being.
Teaching Methodologies (Including Evaluation):
Interrogative, Expository and demonstrative Oral presentation of programmatic content. Active / participatory methodology, supported by audiovisual media. Bibliographical research work with the support of the teacher. Simulation in laboratory with analysis, interpretation and discussion of results. Evaluation: The evaluation of the curricular unit follows the one established in the Academic Regulations for the operation of the Undergraduate and Integrated Master Programs of UFP Theoretical: Two written evaluation tests. Practice: Two individual practical assessment tests. Final classification: CF = [((T1 + T2) / 2) x0.8] + [((P1 + P2) / 2) x0.2] The student must obtain all ECTS in order to obtain their approval. It is a regulatory condition for the approval of the student the attendance of 50% of the theoretical classes as well as 80% of the practical classes.
Demonstration of the Coherence between the Teaching Methodologies and the Learning Outcomes:
In the course of theoretical classes, the need to analyze and reflect on new concepts implies the use of expository and interrogative methodologies, leaving room for the active participation of students in order to sediment the new knowledge by associating them with established ideas. The simulation of practical procedures of microbiology allows to consolidate the knowledge of the theoretical component through the scientific experimentation allowing to add new levels of understanding. The practical component also has the virtue of exposing students to the reality of the existence of microorganisms as well as their survival capacities in our ecosystem. This exhibition intends that students understand the need for interaction and control of microorganisms in the development of their professional life. The realization of two moments of theoretical evaluation allows to validate the acquisition of knowledge, as well as to verify the evolution of the students in the capacity to apply the acquired knowledge. The evaluation performed in laboratory context, through practical tests, allows to confirm the technical competence in the execution of the laboratory procedures as well as to identify the level of precession of the risks associated with the different procedures.
Reading:
Ferreira, W.F.C. and Sousa, J.C., Lima, N. – Microbiologia – LIDEL, 2010 Joanne M. Willey, Linda M. Sherwood, Christopher J. Woolverton – Prescott's Microbiology – McGraw-Hill, 10ª edição, 2016. Sousa, J.C. – Antibióticos volume 1 – Edições UFP, 2016. Sousa, J.C., Cerqueira, F., Abreu, C. – Microbiologia. Protocolos laboratoriais, 2ª edição– Edições UFP, 2012.